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Carprofen

CPN
63000198

Date Published
3.11.2009

Date Revised
6.19.2020

GENERAL DESCRIPTION

Carprofen is an oral nonsteroidal anti-inflammatory drug (NSAID) that is used in dogs to control pain and inflammation due to trauma, surgery, injuries, and osteoarthritis (OA). This medication is for use in dogs only. While Carprofen is not a cure for osteoarthritis, it can control the pain and inflammation of this debilitating disease and improve your pet’s mobility. Carprofen is available as a caplet, flavored tablet or chewable tablet.

 

WHAT IS THIS DRUG?

    Carprofen is a nonsteroidal anti-inflammatory drug (NSAID). Given by mouth.

     

    REASONS FOR PRESCRIBING:

        • Commonly used to reduce pain and inflammation from osteoarthritis in dogs (signs include limping, lameness, stiffness, decreased movement of joints, difficulty in performing activities and decreased activity or exercise)

        • Commonly used to reduce pain and inflammation following surgery (e.g. for surgeries such as spays, ear procedures, dentistry or orthopedic repairs)

        • Your veterinarian may administer injectable Carprofen in the clinic and recommend that you follow up with the oral formulation for several days at home.

       

       

      WHAT DOGS SHOULD NOT TAKE THIS MEDICATION?

          • This medication should not be used in cats

          • This medication should not be used in animals with liver or kidney disease

          • This medication should not be used in animals with active gastrointestinal disease such as inflammatory bowel disease or ulcerations

          • This medication should not be used in animals with bleeding disorders (e.g. von Willebrand’s disease or thrombocytopenia) or animals that require future surgery

          • This medication should not be used in pediatric patients

          • This medication should be used with caution in geriatric animals or pets with pre-existing chronic disease

          • This medication should be used with caution in animals with a history of heart disease

          • Safety in animals that are intended for breeding, pregnant or nursing has not been established

          • Animals with a known hypersensitivity or allergy to this drug should not take this medication

          • Animals with a known hypersensitivity or allergy to aspirin or other NSAIDs should not take this medication

         

        Directions

        • The injectable formulation of Carprofen is often given in the safety of a veterinary hospital with adequate patient monitoring and is rarely prescribed for use at home.

        • For oral formulations, read and follow the prescription label carefully.

        • Give the exact amount prescribed and only as often as directed.

        • Give this medication for as long as your veterinarian directs. Do not skip doses or stop giving the medication without consulting your veterinarian. The length of use, frequency of administration, and expected improvement is dependent upon your pet’s diagnosis, clinical response, and initial reason for use.

        • Baseline blood work and urinalysis is often recommended to assess your pet’s general health before starting this drug. Periodic blood work and urinalysis will be required to monitor this medication’s effects on the body. Dose adjustments or changes to the dosage schedule may be made based upon these results and an assessment of how your dog is responding clinically.

        • Carprofen should be given by mouth with or without food.

        • While Carprofen is not a cure for osteoarthritis, it can relieve the pain and inflammation of OA and improve your dog’s mobility. Response varies from dog to dog but can be quite dramatic. In most dogs, improvement can be seen in a matter of days.

         

        • If Carprofen is discontinued or not given as directed, your dog’s pain and inflammation may come back.

         

        • Do not give this medication with any other over the counter medications that are used for treating pain without consulting your veterinarian.

         

        • This medication will take effect quickly, in about 1 to 2 hours. Improvement in clinical signs should follow.

         

        • Call ahead for refills.

         

        • Ideally give this medication at the same time every day.

        What if a dose is missed?

        If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

         

        Talk to your veterinarian about:

        • Common signs of pain and inflammation in your pet
        • Common signs of osteoarthritis such as: limping or lameness, stiffness, decreased joint movement, decreased activity, reluctance to stand, climb stairs, jump or run or difficulty in performing these activities
        • The importance of weight control and exercise in the management of arthritis
        • When your pet will need to be rechecked
        • What tests may need to be performed prior to and during treatment with this drug
        • What are the risks and benefits of using this drug

         

        Tell your veterinarian about:

        • If your pet has experienced side effects on other drugs/products
        • If your pet has experienced digestive upset now or ever
        • A bleeding disorder (for example, von Willebrand’s disease)
        • If your pet has experienced liver or kidney disease now or ever
        • If your pet has experienced any other medical problems or allergies now or ever
        • All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet’s medications can be given together.
        • If your pet is pregnant, nursing or if you plan to breed your pet

         

        Store in a tight, light resistant, childproof container at room temperature away from heat and direct sunlight. Keep this and all medication out of reach of children and pets. Call your physician immediately if you accidentally take this product. For use in dogs only. Do not use in cats.

         

        • Serious side effects can occur with or without warning and in rare situations result in death. Treatment goals often include the shortest duration of treatment or lowest effective dose consistent with a positive response in order to avoid adverse effects.

           

          • This medication can affect the gastrointestinal system causing loss of appetite, nausea, vomiting, stomach ulcers, perforations and diarrhea
          • This medication can cause a change in bowel movements (such as diarrhea or black, tarry or bloody stools)
          • This medication can affect the liver and kidneys, common clinical symptoms could include increased drinking, increased urination and yellowing of the skin (jaundice)
          • This medication can cause changes in behavior (such as lethargy, increased activity level, incoordination, seizure and aggression)
            If these symptoms persist or you notice anything else unusual, it is important to stop therapy and contact your veterinarian
          • This short-acting medication should stop working within 24 hours, although effects may last longer in pets with liver or kidney disease

           

        • Yes, but possible interactions may occur when giving Carprofen in conjunction with ACE inhibitors (benazepril, enalapril), anticoagulants (coumarin, heparin), anti-inflammatory agents (other NSAIDs), aspirin, corticosteroids, cyclosporin, dacarbazine, desmopressin, digoxin, dinoprost, furosemide, insulin, methotrexate, phenobarbital, phenytoin, probenecid, rifampin, salicylates, sulfonamides, sulfonylurea antidiabetic agents, tricyclic antidepressants (clomipramine) and valproic acid
        • Drugs other than those listed may also interact with Carprofen
        • Do not give new food or medications without first talking to your veterinarian
        • If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.

        Contact your veterinarian immediately if your cat has accidentally received this medication. Contact your veterinarian immediately if your pet receives more than the prescribed amount.

         

        Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment. It is important to periodically discuss your dog’s response to Carprofen at regular check ups. Your veterinarian will best determine if your dog is responding as expected and if your dog should continue receiving Carprofen. As with all prescribed medicines, Carprofen should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed. This is just a summary of information about Carprofen. If you have any questions or concerns about Carprofen, osteoarthritis, post-operative pain or the condition for which it was prescribed, please contact your veterinarian.

         

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